B.Pharmacy 6th Semester Medicinal Chemistry 3 Notes & Important Question Answer
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Medicinal chemistry 6th Sem Notes |
Medicinal Chemistry 3 - Unit 1
Antibiotics
Historical background, Nomenclature, Stereochemistry, Structure activity relationship, Chemical degradation classification and important products of the following classes.
- β-Lactam antibiotics: Penicillin, Cepholosporins, β- Lactamase inhibitors, Monobactams
- Aminoglycosides: Streptomycin, Neomycin, Kanamycin
- Tetracyclines: Tetracycline,Oxytetracycline, Chlortetracycline, Minocycline, Doxycycline
Medicinal Chemistry 3 - Unit 2
Antibiotics
Historical background, Nomenclature, Stereochemistry, Structure activity relationship, Chemical degradation classification and important products of the following classes.
- Macrolide: Erythromycin Clarithromycin, Azithromycin.
- Miscellaneous: Chloramphenicol*, Clindamycin.
- Prodrugs: Basic concepts and application of prodrugs design.
- Antimalarials: Etiology of malaria. Quinolines: SAR, Quinine sulphate, Chloroquine\*, Amodiaquine, Primaquine phosphate, Pamaquine\*, Quinacrine hydrochloride, Mefloquine. Biguanides and dihydro triazines: Cycloguanil pamoate, Proguanil.
- Miscellaneous: Pyrimethamine, Artesunete, Artemether, Atovoquone.
Medicinal Chemistry 3 - Unit 3
Anti-tubercular Agents
- Synthetic anti tubercular agents: Isoniozid\*, Ethionamide, Ethambutol, Pyrazinamide, Para amino salicylic acid.*
- Anti tubercular antibiotics: Rifampicin, Rifabutin, Cycloserine Streptomycine, Capreomycin sulphate.
Urinary tract anti-infective agents
- Quinolones: SAR of quinolones, Nalidixic Acid,Norfloxacin, Enoxacin, Ciprofloxacin\*, Ofloxacin, Lomefloxacin, Sparfloxacin, Gatifloxacin, Moxifloxacin
- Miscellaneous: Furazolidine, Nitrofurantoin\*, Methanamine
Antiviral agents:
- Amantadine hydrochloride, Rimantadine hydrochloride, Idoxuridine trifluoride, Acyclovir\*, Gancyclovir, Zidovudine, Didanosine, Zalcitabine, Lamivudine, Loviride, Delavirding, Ribavirin, Saquinavir, Indinavir, Ritonavir.
- Notes Pdf :- Click Here
Medicinal Chemistry 3 - Unit 4
Antifungal agents:
- Antifungal antibiotics: Amphotericin-B, Nystatin, Natamycin, Griseofulvin.
- Synthetic Antifungal agents: Clotrimazole, Econazole, Butoconazole, Oxiconazole Tioconazole, Miconazole*, Ketoconazole*, Terconazole, Itraconazole, Fluconazole, Naftifine hydrochloride, Tolnaftate.*
- Anti-protozoal Agents: Metronidazole*, Tinidazole, Ornidazole, Diloxanide, Iodoquinol, Pentamidine Isethionate, Atovaquone, Eflornithine.
- Anthelmintic: Diethylcarbamazine citrate*, Thiabendazole, Mebendazole*, Albendazole, Niclosamide, Oxamniquine, Praziquantel, Ivermectin.
Sulphonamides and Sulfones
- Historical development, chemistry, classification and SAR of Sulfonamides: Sulphamethizole, Sulfisoxazole, Sulphamethizine, Sulfacetamide*,
- Sulphapyridine, Sulfamethoxaole*, Sulphadiazine, Mefenide acetate, Sulfasalazine.
Medicinal Chemistry 3 - Unit 5
Introduction to Drug Design
- Various approaches used in drug design.
- Physicochemical parameters used in quantitative structure activity
- relationship (QSAR) such as partition coefficient, Hammet’s electronic
- parameter, Tafts steric parameter and Hansch analysis.
- Pharmacophore modeling and docking techniques. Combinatorial Chemistry: Concept and applications
Combinatorial Chemistry:
- Concept And Applications of combinatorial chemistry: Solid phase and solution phase synthesis.
Medicinal Chemistry 3 book PDF Downloading Link
- Medicinal Chemistry III Nirali Publication Full Book PDF:- Click Here
- Medicinal Chemistry III PV Publication Full Book PDF:- Click Here
- Medicinal Chemistry III Thakur Publication Full Book PDF:- Click Here
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