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B.Pharmacy 4th Semester Pharmaceutical Organic Chemistry 3 Notes & Important Question Answer

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B.Pharmacy 4th Semester Pharmaceutical Organic Chemistry 3 Notes


Pharmaceutical Organic Chemistry 3 - Unit 1

Optical Isomerism –

  • Optical activity, enantiomerism, diastereoisomerism, meso compounds
  • Elements of symmetry, chiral and achiral molecules
  • DL system of nomenclature of optical isomers, sequence rules, RS system of nomenclature of optical isomers
  • Reactions of chiral molecules
  • Racemic modification and resolution of racemic mixture.
  • Asymmetric synthesis: partial and absolute

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B.pharma 4th Sem  Pharmaceutical Organic Chemistry 3 Unit 1 Important Topics PDF:- Click Here

Pharmaceutical Organic Chemistry 3 - Unit 2

Geometrical isomerism

  • Nomenclature of geometrical isomers (Cis Trans, EZ, Syn Anti systems)
  • Methods of determination of configuration of geometrical isomers.
  • Conformational isomerism in Ethane, n-Butane and Cyclohexane.
  • Stereo isomerism in biphenyl compounds (Atropisomerism) and conditions for optical activity.
  • Stereospecific and stereoselective reactions

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B.pharma 4th Sem  Pharmaceutical Organic Chemistry 3 Unit 2 Important Topics PDF:- Click Here

Pharmaceutical Organic Chemistry 3 - Unit 3

Heterocyclic compounds:

  • Nomenclature and classification
  • Synthesis, reactions and medicinal uses of following compounds/derivatives
  • Pyrrole, Furan, and Thiophene
  • Relative aromaticity and reactivity of Pyrrole, Furan and Thiophene

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B.pharma 4th Sem  Pharmaceutical Organic Chemistry 3 Unit 3 Important Topics PDF:- Click Here

Pharmaceutical Organic Chemistry 3 - Unit 4

Synthesis, reactions and medicinal uses of following compounds/derivatives

  • Pyrazole, Imidazole, Oxazole and Thiazole.
  • Pyridine, Quinoline, Isoquinoline, Acridine and Indole. Basicity of pyridine
  • Synthesis and medicinal uses of Pyrimidine, Purine, azepines and their derivatives


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B.pharma 4th Sem  Pharmaceutical Organic Chemistry 3 Unit 4 Important Topics PDF:- Click Here


Pharmaceutical Organic Chemistry 3 - Unit 5

Reactions of synthetic importance

  • Metal hydride reduction (NaBH₄ and LiAlH₄), Clemmensen reduction, Birch reduction, Wolff Kishner reduction.
  • Oppenauer-oxidation and Dakin reaction.
  • Beckmanns rearrangement and Schmidt rearrangement.
  • Claisen-Schmidt condensation


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B.pharma 4th Sem  Pharmaceutical Organic Chemistry 3 Unit 5 Important Topics PDF:- Click Here

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